E.Z. Blumenthal, A. Horani and S. Frenkel

Invest Ophthalmol Vis Sci 2004;45: E-Abstract 3311. © 2004 ARVO 3311 – B946
Dept of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel
Commercial Relationships: E.Z. Blumenthal, Laser Diagnostic Technologies F; A. Horani, None; S. Frenkel, None.
Grant Identification: none


PURPOSE: Scanning laser polarimetry is routinely performed through a non–dilated pupil, since scanning through dilated pupils might contribute to off–axis scanning, and hence, erroneous cornea compensation, reducing test accuracy and reproducibility. We tested the feasibility and reproducibility of scanning through dilated pupils.

METHODS: One eye each, of 36 subjects (12 normal, 12 glaucoma suspects and 12 glaucoma patients) was scanned using the GDx with a variable cornea compensator (GDx–VCC). Two scans prior to, and two scans after dilation were performed on each study eye, resetting the cornea compensation prior to each of the scans. Each of 5 GDx parameters was evaluated separately, comparing the two pre–dilation to the two post–dilation scans.

RESULTS: Of the 5 GDx–VCC parameters evaluated, none showed a statistically significant difference when comparing the pre– to the post–dilation measurements. The two groups showed a high pre– to post–dilation correlation: 98%, 98%, 98%, 93%, and 95% for The Number, TSNIT Avg, TSNIT SD, Superior Avg, and Inferior Avg, respectively. Under 5% of the measurement variability was attributed to changes in pupil size (R–squared: 0.024 to 0.047). Stratifying the data by diagnostic groups yielded similar results.

CONCLUSIONS: Pharmacological mydriasis does not appear to significantly alter the RNFL measurements acquired using the GX–VCC instrument. Scanning dilated patients using the GDx–VCC produced results found to be comparable to scans achieved in the same eyes prior to dilation.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • clinical (human) or epidemiologic studies: systems/equipment/techniques

Glaucoma & Cataract:



This website was written by Prof. Eytan Blumenthal, to better understand glaucoma & cataract. This information should not replace medical consultation.

Related Posts

Risk Factors and Incidence of Ocular Hypertension After Penetrating Keratoplasty
Faik Oruc¸oglu, MD, Eytan Z. Blumenthal, MD, Joseph Frucht-Pery, MD, and Abraham Solomon, MD Journal of Glaucoma. 2013 Feb 19. Kudret Eye Hospital, Istanbul, Turkey Department of Ophthalmology, Hadassah-Hebrew...
List of Publications- by Prof. Eytan Blumenthal
ORIGINAL RESEARCH PAPERS Blumenthal EZ. Adjusting the slit-lamp oculars: An unnecessary burden or a must?  Survey of Ophthalmology 1995;40(3):225-228. Abstract Full-text (PDF) Blumenthal EZ, Serpetopoulos...
Adjusting The Slit-Lamp Oculars: An Unnecessary Burden Or A Must?
Blumenthal EZ. Surv Ophthalmol. 1995 Nov-Dec;40(3):225-8. Department of Opthalmology, Hadassah University Hospital, Jerusalem, Israel. ABSTRACT: Adjusting the slit-lamp eyepiece rings is perceived by some...
On Focusing The Slit-Lamp: Part I. An Inaccurate Ocular Setting--What Is There To Lose?
Blumenthal EZ, Serpetopoulos CN. Surv Ophthalmol. 1998 Jan-Feb;42(4):351-4. Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel. ABSTRACT: Adjustments of the diopter rings on the...
Early Transient Visual Acuity Loss After Lasik Due To Steroid-Induced Elevation Of Intraocular Pressure
Frucht-Pery J, Landau D, Raiskup F, Orucov F, Strassman E, Blumenthal EZ, Solomon A. J Refract Surg. 2007 Mar;23(3):244-51. Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem,...